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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

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Related Experiment Video

Updated: Jun 26, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

Soft tissue sarcomas: current management and future directions.

Robert J Kenney1, Richard Cheney, Margaret A Stull

  • 1Department of Surgery, University of Missouri-Kansas City, and Department of Diagnostic Radiology, St. Luke's Hospital of Kansas City, 2301 Holmes, Kansas City, MO 64108, USA.

The Surgical Clinics of North America
|February 3, 2009
PubMed
Summary
This summary is machine-generated.

This review covers the latest in soft tissue sarcoma diagnosis and treatment, emphasizing surgical standards and future therapeutic directions for this rare cancer.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiology

Background:

  • Soft tissue sarcomas are a heterogeneous group of malignant tumors.
  • Accurate diagnosis and staging are critical for effective management.
  • Treatment requires a multidisciplinary approach.

Purpose of the Study:

  • To provide an updated review of the diagnosis and treatment of soft tissue sarcomas.
  • To highlight current standards in surgical management.
  • To discuss future directions in sarcoma therapy.

Main Methods:

  • Comprehensive literature review of recent advancements.
  • Analysis of current diagnostic modalities including imaging and tissue sampling.
  • Evaluation of established and emerging treatment strategies.

Main Results:

  • Current diagnostic techniques ensure precise staging.
  • Surgical resection remains a cornerstone of treatment.
  • Multimodal therapy is often necessary for optimal outcomes.

Conclusions:

  • Adherence to current surgical standards improves patient outcomes.
  • Ongoing research is paving the way for novel therapeutic options.
  • Continued research is essential for advancing soft tissue sarcoma care.