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Updated: Jun 25, 2026

Rapid Generation of Amyloid from Native Proteins In vitro
Published on: December 5, 2013
[Secondary amyloidosis in Crohn's disease]
S Seijo Ríos1, M Barreiro de Acosta, B Vieites Pérez-Quintela
1Servicios de Aparato Digestivo, Hospital Clínico Universitario de Santiago, Santiago de Compostela, A Coruña. susana-seijo@hotmail.com
Abstract:
Amyloidosis is a clinical entity that results from the deposition of an extracellular protein material that causes disruption in the normal architecture of multiple organs and tissues, and impairs their function. Secondary amyloidosis is a rare but serious complication that may worsen the prognosis of patients with cancer, infection or chronic inflammatory disease, including inflammatory bowel disease, particularly Crohn's disease. We report two cases of Crohn's disease associated with secondary amyloidosis.
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