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Taurine protects immature cerebellar granullar neurons against acute alcohol administration
Andrey G Taranukhin1, Elena Y Taranukhina, Irina M Djatchkova
1Brain Research Center, University of Tampere Medical School, Finland.
Advances in Experimental Medicine and Biology
|February 26, 2009
Abstract:
Acute ethanol administration causes extensive apoptosis throughout the nervous system. We studied the protective effect of taurine on alcohol-induced apoptosis in the cerebellum of developing mice. Taurine rescued a part of immature neurons by markedly reducing caspase-3 immunoreactivity and the number of TUNEL-positive cells in most cerebellar lobules.
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