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Evaluation of the Chem 1 analyzer.
1Servei d'Analisis Clíniques, Hospital Germans Trías i Pujol, Barcelona, Spain.
Annales De Biologie Clinique
|January 1, 1991
Summary
The Technicon Chem 1 analyser shows good accuracy for eighteen clinical chemistry tests. However, interferences from hemoglobin, bilirubin, and turbidity affect results for urate, creatinine, and AST.
Area of Science:
- Clinical Chemistry
- Laboratory Medicine
- Analytical Chemistry
Background:
- The Technicon Chem 1 analyser is a selective multitest system.
- Standardized evaluation protocols are crucial for clinical laboratory instruments.
Purpose of the Study:
- To evaluate the performance of the Technicon Chem 1 analyser.
- To assess its suitability for routine clinical laboratory use.
Main Methods:
- Evaluation followed guidelines from Spanish, European, and French clinical laboratory societies.
- The study included routine conditions, interference assessment, and practicability.
- Imprecision and inaccuracy of eighteen constituents were measured.
Main Results:
- Within-run imprecision ranged from 0.6% to 4.7% (CV).
- Between-run imprecision ranged from 1.6% to 5.5% (CV).
- Positive interferences were observed for urate (hemoglobin), creatinine (turbidity), and AST (turbidity). Negative interferences were noted for creatinine (bilirubin) and urate/urea (turbidity).
Conclusions:
- The Technicon Chem 1 analyser demonstrates good relative inaccuracy for most constituents.
- Potential interferences from hemoglobin, bilirubin, and turbidity require careful consideration during analysis.