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Updated: Jun 24, 2026

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma

Published on: May 24, 2024

Adjuvant therapy.

Wolfgang Wick¹, Michael Weller

¹Department of Neuro-Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, Heidelberg 69120, Germany. wolfgang.wick@med.uni-heidelberg.de

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer

|March 27, 2009

Summary

This summary is machine-generated.

This chapter explores glioma treatment options beyond surgery and radiotherapy, focusing on chemotherapy strategies for all World Health Organization (WHO) grades. It details primary treatments and options for recurrent gliomas.

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Last Updated: Jun 24, 2026

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma

Published on: May 24, 2024

Area of Science:

Neuro-oncology
Medical therapy

Background:

Gliomas are primary brain tumors with varied treatment responses.
Current therapeutic strategies often involve surgery and radiotherapy.
Recurrent gliomas present significant treatment challenges.

Purpose of the Study:

To outline non-surgical and non-radiotherapeutic strategies for glioma management.
To detail the role of chemotherapy in primary and recurrent glioma treatment.
To cover all World Health Organization (WHO) grades of glioma.

Main Methods:

Review of therapeutic strategies for gliomas.
Focus on chemotherapy as a primary or adjuvant treatment modality.
Discussion of treatment options at glioma recurrence.

Main Results:

Chemotherapy is a key therapeutic option for gliomas.
It can be used as a first-line treatment post-diagnosis and pre-radiotherapy.
Chemotherapy is crucial for managing recurrent gliomas after surgery and radiotherapy.

Conclusions:

Chemotherapy offers versatile therapeutic strategies for gliomas of all WHO grades.
It plays a vital role in both initial management and treatment of recurrent disease.
This chapter provides a comprehensive overview of non-surgical and non-radiotherapeutic interventions.