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Updated: Jun 24, 2026
06:54
A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice
Published on: June 22, 2022
[Neuroprotective effects of afobazole in a hemorrhagic stroke model]
Eksperimental'Naia I Klinicheskaia Farmakologiia
|April 2, 2009
Abstract:
The model of posttraumatic hematoma was used to imitate the condition of hemorrhagic stroke in rats. Afobazole (5-ethoxy-2-[2-(morpholino)-ethylthio] benzimidazole dihydrochloride) administered in doses of 0.1 and 1.0 mg/kg intraperitoneally for 14 days was shown to be able to decrease the pathological manifestations of this model. Afobazole administration decreased mortality and the neurological deficits, including motor discoordination, and improve the learning and memory.
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