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Alopecia areata: evidence-based treatments
Seema Garg1, Andrew G Messenger
1Department of Dermatology, Royal Hallamshire Hospital, Sheffield, United Kingdom.
Seminars in Cutaneous Medicine and Surgery
|April 4, 2009
Summary
Alopecia areata causes nonscarring hair loss and psychological distress. This review examines effective treatments like corticosteroids and PUVA, noting limited long-term efficacy data.
Area of Science:
- Dermatology
- Immunology
Background:
- Alopecia areata is a common autoimmune condition causing nonscarring hair loss.
- Hair loss can be patchy, total (alopecia totalis), or affect the whole body (alopecia universalis).
- The condition can lead to significant psychological distress due to its unpredictable course and potential for relapse.
Purpose of the Study:
- To review the evidence for commonly used treatments for alopecia areata.
- To inform patients about treatment options, their side effects, and the unpredictable nature of the condition.
Main Methods:
- Review of existing evidence for treatments including corticosteroids, topical sensitizers, PUVA, minoxidil, and dithranol.
- Assessment of treatment efficacy and impact on quality of life.
Main Results:
- Several treatments can stimulate hair growth in alopecia areata.
- Limited data exists on the long-term efficacy and quality of life impact of these treatments.
Conclusions:
- Counseling patients on the unpredictable nature of alopecia areata and available treatments is crucial.
- Further research is needed on the long-term efficacy and quality of life outcomes of alopecia areata treatments.
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