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Updated: Jun 23, 2026

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Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
Published on: March 8, 2019
Hydrogel intraocular lens exchange: five-year experience.
P E Theoulakis1, C K Brinkmann, I K Petropoulos
1University Eye Clinic, Inselspital Bern, Bern, Switzerland.
Summary
Exchange of opacified hydrogel intraocular lenses (IOLs) improved visual acuity but carried risks. Careful patient selection and informed consent are crucial due to potential complications.
Area of Science:
- Ophthalmology
- Biomaterials Science
Background:
- Opacified hydrogel intraocular lenses (IOLs) can negatively impact visual function.
- Evaluating the outcomes of IOL exchange is critical for patient care.
Purpose of the Study:
- To assess visual acuity changes after opacified hydrogel IOL exchange.
- To determine the incidence of complications associated with this procedure.
Main Methods:
- 55 patients with opacified hydrogel IOLs underwent exchange.
- Preoperative and postoperative best corrected visual acuity (BCVA) were compared.
- Intraoperative and postoperative complications were meticulously recorded over a 3- to 24-month follow-up period.
Main Results:
- Mean BCVA significantly improved post-exchange, with 72.7% reporting better vision.
- The procedure was uneventful in 54.5% of cases.
- Complications included cystoid macular edema (27.3%), retained haptics (14.5%), and partial zonular dehiscence (18.2%).
Conclusions:
- Opacified hydrogel IOL exchange can enhance visual acuity.
- Significant postoperative complications can occur, potentially limiting expected outcomes.
- Thorough informed consent is essential due to the risks involved.
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