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Construction and characterization of melanocortin-2 and -4 receptor chimeras

Krista R Wilson1, Bettina Proneth, Hendrik Luesch

  • 1Department of Medicinal Chemistry, University of Florida, Gainesville, FL 32610, USA.

Advances in Experimental Medicine and Biology
|April 30, 2009
PubMed
Abstract

No abstract available in PubMed .

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The pharmacological actions of acetylcholine are elicited via its binding to two families of cholinergic receptors or cholinoceptors, namely, muscarinic and nicotinic receptors. Muscarinic receptors are G protein-coupled receptors and have five subtypes, M1–M5. All mAChR subtypes are activated by acetylcholine and blocked by the antagonist, atropine. 
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