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Hepatic and skeletal metastases from primary intracranial atypical meningioma
Asghar H Asghar1, Humera Mahmood, Mohammad Faheem
1Department of Radiotherapy, NORI Hospital, Islamabad. quaidian@yahoo.com
Abstract:
Meningioma constitutes 27% of primary CNS tumours. It rarely metastasizes to distant sites (< 0.1%). Here, we present a case report of primary atypical intracranial meningioma metastasizing to liver and bone after 4 years of surgery and postoperative radiotherapy presenting with multiple episodes of hypoglycemia.
Insights
A rare case of atypical intracranial meningioma metastasized to the liver and bone four years post-surgery. This unusual presentation highlights the importance of monitoring for distant metastases in meningioma patients.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Meningiomas are the most common primary tumors of the central nervous system (CNS), accounting for 27% of all intracranial neoplasms.
- Distant metastasis from meningioma is exceedingly rare, occurring in less than 0.1% of cases.
Observation:
- This report details a unique case of a primary atypical intracranial meningioma.
- The patient underwent surgery and postoperative radiotherapy.
- Four years after treatment, the patient developed hypoglycemia and presented with metastatic disease.
Findings:
- The atypical meningioma metastasized to distant sites, specifically the liver and bone.
- The metastatic presentation was associated with recurrent episodes of hypoglycemia.
Implications:
- This case underscores the potential for rare distant metastasis of atypical meningiomas.
- It highlights the need for vigilance and long-term surveillance in patients treated for meningioma, particularly atypical variants.
- The association with hypoglycemia warrants further investigation into the paraneoplastic effects of meningioma metastasis.
