[Aprotinin scintigraphy in amyloidosis]
Ate Haraldsen1, Anni Eskild-Jensen, Jørgen Frøkiaer
1Afdelingen for Klinisk Fysiologi og Nuklearmedicin, Arhus Universitetshospital, Skejby, DK-8200 Arhus N.
Abstract:
Amyloidosis is a disease characterized by protein deposition (amyloid) in THE extracellular matrix leading to organ dysfunction and death. New treatment modalities have emphasized the need for accurate and early diagnosis. Aprotinin scintigraphy is a radionuclide imaging technique in which the localisation and extent of amyloid deposits are visualized. It is specific and sensitive in detecting cardiac amyloidosis, which is associated with a poor prognosis. In addition, aprotinin scintigraphy appears to be a useful tool for the monitoring of disease progression and treatment efficacy.

