[Neuroimaging studies in borderline personality disorder].

Area of Science:

• Neuroscience
• Psychiatry
• Medical Imaging

Context:

• Borderline personality disorder (BPD) is the most prevalent personality disorder, affecting 0.2-1.8% of the population, predominantly women.
• Despite its prevalence and known biological correlates, neuroimaging research on BPD remains limited.
• Existing research suggests potential dual cerebral involvement, particularly in frontal and limbic circuits.

Purpose:

• To review current neuroimaging findings in Borderline personality disorder.
• To explore the relationship between neurobiological alterations, stress, and BPD.
• To highlight the application of advanced neuroimaging techniques in BPD research.

Summary:

• BPD is characterized by emotional instability, polarized thinking, and interpersonal chaos.
• Neuroimaging suggests frontal and limbic circuit dysfunction in BPD, potentially linked to serotonergic deficits.
• Traumatic experiences and stress are implicated in BPD's neurobiological underpinnings.

Impact:

• Advances understanding of BPD's neurobiological basis.
• Provides a foundation for future neuroimaging research in BPD.
• May inform the development of targeted diagnostic and therapeutic strategies for BPD.