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Updated: Jun 21, 2026

09:06
MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as a Novel Detection and Quantification Method
Published on: October 7, 2025
Colorimetric detection of microRNA and RNase H activity in homogeneous solution with cationic polythiophene
Yali Zhang1, Zhengping Li, Yongqiang Cheng
1Key Laboratory of Medicine Chemistry and Molecular Diagnosis, Ministry of Education, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, Hebei Province, PR China.
Abstract:
A colorimetric assay for convenient detection of miRNA and RNase H activity was established in a homogeneous and label-free manner based on conformational and colorimetric changes of a polythiophene derivative (PMNT) in the duplex of DNA/PMNT and triplex of DNA/miRNA/PMNT.

