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Published on: May 26, 2015
Active two-channel 0.035'' guidewire for interventional cardiovascular MRI
Ozgur Kocaturk1, Ann H Kim, Christina E Saikus
1Translational Medicine Branch, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1061, USA. kocaturko@nhlbi.nih.gov
Journal of Magnetic Resonance Imaging : JMRI
|July 25, 2009
Summary
This study introduces a novel active guidewire for magnetic resonance imaging (MRI) procedures. The MRI-compatible guidewire offers enhanced visibility and comparable mechanical performance to traditional devices.
Area of Science:
- Biomedical Engineering
- Medical Imaging
- Interventional Radiology
Background:
- Interventional MRI procedures require highly visible intravascular instruments.
- Current guidewires often lack sufficient conspicuity under MRI.
- Distinguishing instruments from surrounding tissues is crucial for procedural accuracy.
Purpose of the Study:
- To develop a clinical-grade, active guidewire for MRI.
- Enhance guidewire visibility during magnetic resonance imaging.
- Ensure favorable mechanical characteristics for interventional MRI.
Main Methods:
- Designed a 0.035-inch guidewire with integrated loop and dipole antennas.
- Evaluated mechanical properties (stiffness, torquability, pushability) against x-ray guidewires.
- Tested MRI performance in vitro and in vivo (swine) at 1.5T.
Main Results:
- Achieved accurate tip localization (0.97 +/- 0.42 mm).
- Provided whole-shaft visibility under MRI conditions.
- Demonstrated mechanical characteristics comparable to commercial guidewires.
Conclusions:
- Developed a conspicuous, clinical-grade active guidewire for MRI.
- The guidewire exhibits mechanical performance suitable for interventional procedures.
- Enables potential for a wider range of real-time MRI-guided interventions.
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