Related Experiment Video
Updated: Jun 21, 2026
08:25
Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
[Skin contact reactions caused by plants]
Duodecim; Laaketieteellinen Aikakauskirja
|August 15, 2009
Summary
Plants can trigger skin and mucosal reactions, including various forms of dermatitis and urticaria. These contact reactions range from irritant and allergic dermatitis to protein contact dermatitis and phytophotodermatitis.
Area of Science:
- Dermatology
- Toxicology
- Botany
Context:
- Plant-induced skin and mucosal reactions are common.
- Diverse clinical presentations occur, affecting both skin and mucous membranes.
Purpose:
- To outline the spectrum of plant-related contact reactions.
- To categorize different types of dermatitis and urticaria caused by plants.
Summary:
- Plants and their products induce various contact reactions, primarily dermatitis (irritant, allergic, airborne allergen-induced).
- Other reactions include allergic and non-allergic contact urticaria, protein contact dermatitis, and phytophotodermatitis.
- Actinic reticuloid, often linked to contact allergy, is also recognized as a plant-induced contact reaction.
Impact:
- Enhances understanding of plant-allergen interactions.
- Provides a classification for diagnosing and managing plant-related dermatological conditions.
- Highlights the broad range of adverse reactions plants can cause.
Related Concept Videos
01:30Drug Toxicity: Allergic Reactions
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
02:06Allergic Reactions
Overview
01:27Allergic Drug Reactions
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
01:25Cell Signaling in Plants
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
02:26Defenses Against Pathogens and Herbivores
Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
01:30Allergic Reactions: Anaphylaxis
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...