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Drug prophylaxis for migraine headaches
1University of Kansas School of Medicine, Wichita.
American Family Physician
|August 1, 1990
Summary
Migraine drug prophylaxis offers significant relief for those with disruptive attacks. A tailored approach combining medication, lifestyle changes, and coping strategies is key for effective migraine management.
Area of Science:
- Neurology
- Pharmacology
Background:
- Migraine headaches cause significant disruption for many patients.
- Prophylactic drug treatment is not universally indicated but can be beneficial.
Purpose of the Study:
- To outline the indications and components of effective migraine drug prophylaxis.
- To discuss the individualized nature of prophylaxis and benefit-risk assessment.
Main Methods:
- Review of current practices in migraine prophylaxis.
- Identification of commonly used and effective prophylactic medications.
Main Results:
- Prophylaxis is most effective as part of a comprehensive plan including trigger avoidance, coping skills, and exercise.
- Beta-adrenergic blockers (e.g., propranolol) are frequently used.
- Other effective options include tricyclic antidepressants, calcium channel blockers, and NSAIDs (e.g., naproxen).
Conclusions:
- Individualized migraine prophylaxis, balancing benefits against side effects, is crucial.
- A multimodal approach enhances the efficacy of drug prophylaxis for migraine management.