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Related Concept Videos

Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...

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Related Experiment Video

Updated: Jun 20, 2026

Quantification of Acanthamoeba spp. Motility
07:33

Quantification of Acanthamoeba spp. Motility

Published on: September 20, 2024

[Acanthamoebal keratitis].

Katri Sarparanta1, Nina Lindbohm, Timo Tervo

  • 1Haartman-instituutti, Helsingin yliopisto.

Duodecim; Laaketieteellinen Aikakauskirja
|September 23, 2009
PubMed
Summary

Acanthamoeba infections, particularly Acanthamoeba keratitis, affect immunocompromised individuals and contact lens wearers. Early diagnosis using in vivo confocal microscopy improves prognosis compared to traditional methods.

Area of Science:

  • Microbiology
  • Ophthalmology
  • Infectious Diseases

Context:

  • Acanthamoebae are opportunistic protists responsible for severe infections.
  • Acanthamoeba keratitis is a serious eye infection, often linked to contact lens use and contaminated water exposure.
  • Impaired corneal defenses increase susceptibility to Acanthamoeba infections.

Purpose:

  • To highlight the significance of Acanthamoeba infections, especially keratitis.
  • To discuss predisposing factors for Acanthamoeba keratitis.
  • To emphasize the importance of timely diagnosis and the role of advanced imaging techniques.

Summary:

  • Acanthamoebae cause opportunistic infections, notably Acanthamoeba keratitis, in immunocompromised patients and others.
  • Risk factors include corneal trauma and contact lens wear with exposure to contaminated water.

Related Experiment Videos

Last Updated: Jun 20, 2026

Quantification of Acanthamoeba spp. Motility
07:33

Quantification of Acanthamoeba spp. Motility

Published on: September 20, 2024

  • Delayed diagnosis and treatment negatively impact outcomes for Acanthamoeba keratitis.
  • Impact:

    • Early detection of Acanthamoeba keratitis is crucial for better patient outcomes.
    • Noninvasive in vivo confocal microscopy offers a faster and earlier diagnostic approach.
    • Improved diagnostic methods aid in managing refractory Acanthamoeba keratitis cases.