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Updated: Jun 20, 2026

Isolation and Characterization of Neutrophils with Anti-Tumor Properties
Published on: June 19, 2015
Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms?
Ingrid Müller1, Markus Munder, Pascale Kropf
1Department of Immunology, Faculty of Medicine, Imperial College London, London W2 1PG, UK.
Abstract:
Polymorphonuclear neutrophils (PMN) are linked invariably to the innate immune response, particularly to the defence against bacterial infection. T lymphocytes are studied mainly in virus infections, the defence against tumours, the development and progression of chronic inflammatory processes, in autoimmune phenomena and in materno-fetal tolerance. There is, however, increasing evidence for communication and interactions between PMN and T cells that we discuss here in the context of different physiological and pathological conditions, including acute and chronic inflammatory disease, defence against tumours, and maintenance of pregnancy.
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