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Updated: Jun 20, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Off-pump versus on-pump coronary artery bypass grafting
Michael E Halkos1, John D Puskas
1Division of Cardiothoracic Surgery, Emory University Hospital-Midtown, Emory University School of Medicine, 550 Peachtree Street, Medical Office Tower, Atlanta, GA 30308, USA.
Abstract:
Off-pump coronary artery bypass is a safe and effective method of coronary revascularization that avoids the use of cardiopulmonary bypass. Randomized trials, typically enrolling low-risk patients, have shown comparable mortality and reduced morbidity between off-pump and on-pump coronary artery bypass. Larger retrospective analyses suggest improved mortality and a lower incidence of adverse events in patients undergoing off-pump coronary artery bypass. This article reviews the available literature comparing outcomes of patients undergoing on- and off-pump coronary artery bypass surgery.
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