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Ocular findings associated with encephalomyelitis caused by Herpesvirus simiae
American Journal of Ophthalmology
|September 1, 1977
Summary
Herpesvirus simiae infection in a monkey handler caused acute encephalomyelitis and vision loss. Ocular complications included vitreous hemorrhage, retinal scarring, and detachment due to a gliovascular band.
Area of Science:
- Ophthalmology
- Virology
- Neurology
Background:
- Herpesvirus simiae (B virus) is a zoonotic pathogen primarily affecting macaques.
- Human infections are rare but can be severe, often resulting from occupational exposure.
Observation:
- A 29-year-old primate handler presented with symptoms of acute encephalomyelitis.
- Serological tests confirmed Herpesvirus simiae infection.
Findings:
- The patient experienced sudden unilateral vision loss on day 32, attributed to vitreous hemorrhage.
- Ophthalmic examination revealed chorioretinal scarring and a gliovascular vitreous band.
- This band subsequently led to localized tractional retinal detachment.
Implications:
- This case highlights the potential for severe ocular manifestations of Herpesvirus simiae infection.
- Prompt diagnosis and management are crucial for preventing vision-threatening complications in high-risk individuals.
- Understanding the pathogenesis of B virus-induced ocular disease is vital for developing targeted therapies.