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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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Superelectrophilic intermediates in nitrogen-directed aromatic borylation

Timothy S De Vries1, Aleksandrs Prokofjevs, Jeremy N Harvey

  • 1Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

Journal of the American Chemical Society
|October 15, 2009
PubMed
Summary

This study introduces novel borylation reactions forming cyclic borenium ions from hydrogen-bridged boron cations. These reactions utilize hydride abstraction and demonstrate unique cyclization pathways, confirmed by spectroscopy and computational analysis.

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