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Updated: Jun 19, 2026
13:08
Quantitative Localization of a Golgi Protein by Imaging Its Center of Fluorescence Mass
Published on: August 10, 2017
Mitotic inheritance of the Golgi complex.
Angela Persico1, Romina Ines Cervigni, Maria Luisa Barretta
1Department of Cell Biology and Oncology, Consorzio Mario Negri Sud, 66030 Santa Maria Imbaro (Chieti), Italy.
FEBS Letters
|November 3, 2009
Summary
Mammalian Golgi complex ribbons fragment during mitosis for cell division. This review explores the mechanisms and significance of Golgi inheritance in dividing cells.
Area of Science:
- Cell Biology
- Molecular Biology
- Organelle Biology
Background:
- The Golgi complex in mammals forms a continuous "Golgi ribbon" structure.
- Mitosis requires Golgi complex fragmentation for proper inheritance into daughter cells.
Purpose of the Study:
- To review recent studies on Golgi complex fragmentation during mitosis.
- To elucidate the molecular mechanisms and biological significance of Golgi inheritance.
Main Methods:
- Review of recent scientific literature.
- Analysis of molecular players involved in Golgi fragmentation.
- Examination of cell cycle regulation and Golgi partitioning.
Main Results:
- Golgi fragmentation is a multi-step process essential for cell division.
- Precise coordination exists between Golgi fragmentation and cell cycle progression.
- Key molecular players regulating this process are being identified.
Conclusions:
- Understanding Golgi inheritance mechanisms is crucial for cell biology.
- Further research will reveal more about the fundamental processes of organelle inheritance.
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