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Updated: Jun 18, 2026

Aplysia Ganglia Preparation for Electrophysiological and Molecular Analyses of Single Neurons
Published on: January 13, 2014
Specific features of molecular postsynaptic excitation processes of different sensory modalities in edible snail
V P Nikitin1, K V Sudakov, V V Sherstnev
1P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow. nikitin.vp@mail.ru
Abstract:
Stimulations of different sensory modalities result in selective activation of second messengers and genes controlled by them in defensive behavior command neurons (LPl-1 and RPl-1) in edible snail. Excitation induced by stimulation of chemoreceptors of snail head results in cAMP accumulation in command neurons and induction of associated transcriptional factors of immediate early gene C/EBP, whereas regulating mechanisms of another sensory input mediating excitation after tactile head stimulation, involve protein kinase C and associated transcriptional factor SRF. These findings reflect specific features of postsynaptic processes providing excitation of different sensory modalities converging to defensive behavior command neurons in edible snails.
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