Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Biological Causes of Schizophrenia

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.

Psychological and Sociocultural Causes of Schizophrenia

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...

Schizophrenia

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...

Stereotype Content Model

Stereotype Content Model

The Stereotype Content Model (SCM) was first proposed by Susan Fiske and her colleagues (Fiske, Cuddy, Glick & Xu, 2002; see also Fiske, 2012 and Fiske, 2017). The SCM specifies that when someone encounters a new group, they will stereotype them based on two metrics: warmth—or that group’s perceived intent, and how likely they are to provide help or inflict harm—and competence—or their ability to carry out that objective. Depending on the warmth-competence categorization, a person will feel...

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Spanish translation and analysis of the metric properties of inpatient satisfaction scale in psychiatry: The Satispsy-22-E.

Psychiatry research·2018

Same author

Emotion processing in joint hypermobility: A potential link to the neural bases of anxiety and related somatic symptoms in collagen anomalies.

European psychiatry : the journal of the Association of European Psychiatrists·2015

Same author

The sufficiency of the HAM-D6 as an outcome instrument in the acute therapy of antidepressants in the outpatient setting.

International journal of psychiatry in clinical practice·2014

Same author

Increased tobacco and alcohol use among women with joint hypermobility: a way to cope with anxiety?

Rheumatology international·2014

Same author

Striatal volume deficits in children with ADHD who present a poor response to methylphenidate.

European child & adolescent psychiatry·2014

Same author

Brain regions related to fear extinction in obsessive-compulsive disorder and its relation to exposure therapy outcome: a morphometric study.

Psychological medicine·2013

Same journal

Mortality Risks in Patients With Schizophrenia in Shanghai: A Longitudinal Cohort Study.

Actas espanolas de psiquiatria·2026

Same journal

Causal Relationship Between Vitamin D and Anxiety and Depression: A Bidirectional Mendelian Randomization Study.

Actas espanolas de psiquiatria·2026

Same journal

Assessment of Mental Health Nurses' Competences: A Scoping Review.

Actas espanolas de psiquiatria·2026

Same journal

Gender Identity and Gender Dysphoria in Autism Spectrum Disorders: A Systematic Review.

Actas espanolas de psiquiatria·2026

Same journal

Bridging Three Decades: Global Self-Harm Trends From 1990-2021 and Projections to 2040.

Actas espanolas de psiquiatria·2026

Same journal

ADHD, Subtypes and Cognitive Performance: WISC-V as a Support Tool for Diagnostic Assessment.

Actas espanolas de psiquiatria·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 18, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

[Somatotype and schizophrenia. A case-control study].

G Pailhez¹, A Rodríguez, J Ariza

¹Institut d'Atenció Psiquiátrica: Salut Mental i Toxicomanies, Hospital del Mar (IMAS), Unidad Docente Universidad Autónoma de Barcelona (UDIMAS). 97590@imas.imim.es

Actas Espanolas De Psiquiatria

|December 5, 2009

Summary

This summary is machine-generated.

Schizophrenia patients showed more varied body types (somatotypes) than healthy individuals, particularly in ectomorphic features. This suggests potential for identifying subtypes within schizophrenia using somatotype analysis.

More Related Videos

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

Related Experiment Videos

Last Updated: Jun 18, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

Area of Science:

Psychiatry and Somatology
Clinical Psychology

Context:

Schizophrenia is a complex mental illness with varied presentations.
Understanding the physical characteristics of patients may offer insights into disease heterogeneity.

Purpose:

To compare the somatotypes of individuals with schizophrenia to healthy controls.
To investigate associations between body type, joint mobility, and psychopathological features in schizophrenia.

Summary:

No significant differences in mean somatotypes were found between schizophrenia patients and controls.
Schizophrenia patients exhibited greater somatotype variability, with a higher prevalence of ectomorphic features.
Specific subtypes of schizophrenia (paranoid, disorganized) showed more homogeneous somatotypes with increased ectomorphism compared to the undifferentiated type.

Impact:

Findings suggest somatotype could serve as a potential risk marker or aid in the nosological classification of mental illnesses.
This research opens avenues for identifying distinct subtypes within schizophrenia based on physical characteristics.