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Dendritic spine and synapse morphological alterations induced by a neural cell adhesion molecule mimetic

Michael Stewart1, Victor Popov, Nikolai Medvedev

  • 1Department of Life Sciences, Faculty of Sciences, The Open University, Walton Hall, Milton Keynes, MK76AA, UK. m.g.stewart@open.ac.uk

Advances in Experimental Medicine and Biology
|December 18, 2009
PubMed
Abstract

No abstract available in PubMed .

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Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
Ig-CAMs exhibit either homophilic binding (to other Ig-CAMs) or heterophilic binding (to other ligands such as integrins). While most Ig-CAMs...

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