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Updated: Jun 17, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Atrial fibrillation in elderly patients]
Pierre-Laurent Massoure1, Frédéric Sacher, Nicolas Derval
1Hôpital cardiologique Haut-Lévêque, CHU de Bordeaux, Pessac, France. plmassoure@aol.com
Insights
Atrial fibrillation (AF) is a common heart rhythm disorder in older adults, increasing stroke risk. Anticoagulation therapy is crucial for managing AF patients, but requires careful assessment of bleeding risks.
Area of Science:
- Cardiology
- Geriatrics
- Pharmacology
Context:
- Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia in the elderly population, with prevalence reaching 6-8% in octogenarians.
- AF is frequently associated with comorbidities such as cardiomyopathy (50%) and hypertension (60%).
- The condition significantly elevates the risk of ischemic stroke, particularly in individuals over 75, with annual rates up to 7%.
Purpose:
- To review the current understanding of atrial fibrillation in the elderly.
- To highlight the therapeutic strategies for managing AF in this demographic, focusing on stroke prevention and rate control.
- To emphasize the importance of risk stratification for antithrombotic therapy and hemorrhage risk assessment.
Summary:
- Antiarrhythmic drugs can help control the cardiac rate in AF patients.
- Antithrombotic therapy, including anticoagulation, is essential for preventing emboli in all AF types.
- Elderly AF patients, often at high or intermediate risk, require systematic evaluation of major hemorrhage risk alongside anticoagulation management.
Impact:
- Provides a concise overview of AF management in the elderly.
- Underscores the critical role of anticoagulation in reducing stroke risk for this vulnerable population.
- Emphasizes the necessity of balancing anticoagulation benefits against potential bleeding complications in geriatric patients.
Abstract:
Atrial fibrillation (AF) is the most common cardiac arrhythmia in elderly patients: its prevalence increases with age up to 6-8% in octogenarians. A cardiomyopathy is associated in 50%, hypertension in 60%. Severity is attributed to the risk of ischaemic stroke with rates increasing up to 7% per year after 75 years old. Quality of life is impaired and associated with numerous comorbidities in the elderly. Antiarrhythmic therapy is useful to slow down cardiac rate in AF. To reduce first or recurrent emboli, antithrombotic therapy is necessary, whatever the type of AF (paroxysmal or permanent). Anticoagulation is the current treatment modality in AF patients at high or intermediate risk, which is the case of most of the elderly patients. Major hemorrhage risk must be systematically evaluated.
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