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LRRTM2 interacts with Neurexin1 and regulates excitatory synapse formation.

Joris de Wit1, Emily Sylwestrak, Matthew L O'Sullivan

  • 1Neurobiology Section, Division of Biology, University of California, San Diego, La Jolla, CA 92093, USA.

Neuron
|January 13, 2010
PubMed
Summary

Leucine-rich repeat transmembrane protein 2 (LRRTM2) regulates excitatory synapse development by interacting with Neurexin1. This interaction is crucial for forming functional excitatory synapses in the brain.

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