Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glial Cells01:04

Glial Cells

Overview
Organization of the Nervous System01:13

Organization of the Nervous System

The nervous system is one of the most complex systems in our body. It is organized into two main divisions: the central nervous system (CNS) and the peripheral nervous system (PNS).
The CNS, comprising the brain and spinal cord, houses billions of neurons. The brain is housed in the skull, while the spinal cord is linked to the brain through the foramen magnum of the occipital bone and is surrounded by the protective structure of the vertebral column. It is responsible for processing various...
Nervous Tissue: Glial Cells01:31

Nervous Tissue: Glial Cells

Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial cells that interact...
Peripheral Nervous System: Ganglia and Nerves01:24

Peripheral Nervous System: Ganglia and Nerves

The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...
What is a Nervous System?01:25

What is a Nervous System?

Overview
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-antigen-targeting T cells in pediatric central nervous system tumors: a phase 1 trial.

Nature medicine·2026
Same author

Transcriptomic Meta-Analysis and Functional Validation Identify Long Non-Coding RNAs as Modulators of Zika Virus-Mediated Oncolysis in Glioblastoma Multiforme Cell Lines.

Cells·2026
Same author

Tempered Optimism: Advances in the Precision Medicine Era for Pediatric Low-Grade Glioma.

Neuro-oncology·2026
Same author

Multi-Institutional Annotated Multiparametric MRI Dataset of Pediatric High-Grade Gliomas.

Radiology. Artificial intelligence·2026
Same author

Comment: The fetal taenia-tela choroidea complex is frequently detectable on MRI when it is needed in the differential diagnosis of posterior fossa abnormalities.

Pediatric radiology·2026
Same author

Clinical and Genetic Characteristics of Free Sialic Acid Storage Disorder.

Journal of inherited metabolic disease·2026
Same journal

Palliative Therapy for Liver and Biliary Neoplasms.

Hematology/oncology clinics of North America·2026
Same journal

Ablative Therapies for Liver Tumors.

Hematology/oncology clinics of North America·2026
Same journal

Pathology of Liver and Biliary Neoplasms.

Hematology/oncology clinics of North America·2026
Same journal

Minimally Invasive Surgery for Liver and Biliary Tract Neoplasms.

Hematology/oncology clinics of North America·2026
Same journal

Surgical Considerations for Primary Liver Neoplasms.

Hematology/oncology clinics of North America·2026
Same journal

Systemic Therapy for Biliary and Liver Neoplasms: Chemotherapy and Immunotherapy.

Hematology/oncology clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Jun 16, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
05:39

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

Central nervous system tumors.

Roger J Packer1, Tobey Macdonald, Gilbert Vezina

  • 1Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, 111 Michigan Avenue, Washington, DC 20010, USA.

Hematology/Oncology Clinics of North America
|February 2, 2010
PubMed
Summary
This summary is machine-generated.

Central nervous system (CNS) tumors are a significant cause of childhood cancer, often presenting with varied symptoms that can delay diagnosis. This article details their presentation, diagnosis, and management in pediatric patients.

More Related Videos

Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting
08:14

Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting

Published on: September 25, 2012

Related Experiment Videos

Last Updated: Jun 16, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
05:39

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting
08:14

Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting

Published on: September 25, 2012

Area of Science:

  • Pediatric Oncology
  • Neuro-oncology
  • Childhood Malignancies

Background:

  • Central nervous system (CNS) tumors represent 15-20% of all pediatric malignancies.
  • Presentation of CNS tumors is highly variable, frequently leading to diagnostic delays.
  • Clinical manifestations depend on tumor growth rate, CNS location, and patient age.

Purpose of the Study:

  • To outline the diverse presentations of CNS tumors in children and adolescents.
  • To describe the diagnostic approaches for pediatric CNS malignancies.
  • To review current management strategies for CNS tumors in pediatric populations.

Main Methods:

  • Review of clinical presentations.
  • Analysis of diagnostic modalities.
  • Synthesis of treatment guidelines.

Main Results:

  • Symptoms are diverse and age-dependent, impacting diagnosis.
  • Location and growth rate significantly influence clinical signs.
  • Timely diagnosis and appropriate management are crucial.

Conclusions:

  • Pediatric CNS tumors require a comprehensive understanding of varied presentations.
  • Multidisciplinary approaches are essential for accurate diagnosis and effective management.
  • Early detection and tailored treatment improve outcomes for children with CNS tumors.