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Fungal keratitis in lattice dystrophy
Samrat Chatterjee1, Deepshikha Agrawal
1Cornea and Anterior Segment Services, MGM Eye Institute, 5th Mile, Vidhan Sabha Road, Raipur, India.
Indian Journal of Ophthalmology
|March 3, 2010
Summary
Lattice dystrophy patients are susceptible to fungal keratitis due to compromised corneas. Prompt treatment with natamycin eye drops successfully healed the infection in this case.
Area of Science:
- Ophthalmology
- Mycology
Background:
- Lattice dystrophy is a hereditary corneal disease characterized by amyloid deposits.
- Patients with lattice dystrophy have a compromised corneal epithelial barrier, increasing susceptibility to infection.
Observation:
- A 57-year-old farmer with lattice dystrophy presented with a month-long corneal ulcer after probable paddy husk injury.
- Corneal scraping revealed pigmented fungal filaments, and culture identified Alternaria alternata.
Findings:
- Fungal keratitis caused by Alternaria alternata was diagnosed.
- Treatment with 5% natamycin eye drops and 1% atropine resulted in complete healing within four weeks.
Implications:
- Corneas affected by lattice dystrophy are prone to recurrent erosions and microbial invasion.
- Early medical attention for trivial trauma and prophylactic topical antibiotics are crucial for managing corneal abrasions in these patients.
