Surgical management of primary osteosarcoma

Area of Science:

• Orthopedic Oncology
• Surgical Innovation
• Pediatric Oncology

Background:

• Osteosarcoma treatment has evolved from amputation to limb-sparing surgery over 30 years.
• Tissue-conserving techniques show favorable outcomes in skeletally mature patients.
• These approaches are increasingly applied to skeletally immature patients.

Purpose of the Study:

• To review current surgical strategies for primary extremity and pelvis osteosarcoma.
• To discuss advancements in tissue preservation and reconstruction methods.
• To address challenges in definitive treatment, including local recurrence and reconstruction complications.

Main Methods:

• Review of contemporary surgical techniques for osteosarcoma.
• Analysis of oncologic and functional outcomes data.
• Discussion of novel biological and nonbiological reconstruction methods.

Main Results:

• Limb-sparing surgery offers favorable oncologic and functional outcomes.
• Refined resection and reconstruction techniques are crucial for optimizing function.
• Long-term outcome data informs current treatment strategies.

Conclusions:

• Current surgical management focuses on precise resection and advanced reconstruction.
• Efforts are ongoing to improve functional outcomes and manage complications.
• Addressing locally recurrent disease remains a key challenge in osteosarcoma treatment.