Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Interaction between calcium antagonists and digoxin].

C Christensen1

  • 1Kolding Sygehus, medicinsk-kardiologisk afsnit B.

Ugeskrift for Laeger
|April 22, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mergers and migrations: drivers of population genetic structure in a captive rhesus macaque colony.

BMC genomics·2026
Same author

Baboon travel progressions as a "social spandrel" in collective animal behaviour.

Behavioral ecology : official journal of the International Society for Behavioral Ecology·2025
Same author

The genomic legacy of selectively breeding rhesus macaques for HIV/AIDS-related research.

bioRxiv : the preprint server for biology·2025
Same author

A scoring system for grading corkscrew claws in dairy cattle.

Veterinary journal (London, England : 1997)·2024
Same author

Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID-19 convalescent plasma clinical trial.

Journal of internal medicine·2020
Same author

A Scalable Cyberinfrastructure for Interactive Visualization of Terascale Microscopy Data.

... New York Scientific Data Summit (NYSDS) : proceedings ...·2017
Same journal

Ugeskrift for laeger·2026
Same journal

[Financial support scheme following a recognised occupational injury].

Ugeskrift for laeger·2026
Same journal

[Foreign body granulomas in the lungs after several years of parenteral nutrition].

Ugeskrift for laeger·2026
Same journal

[Vaginal aids for stress incontinence].

Ugeskrift for laeger·2026
Same journal

[Osteodystrophy in chronic liver disease].

Ugeskrift for laeger·2026
Same journal

[Tympanic membrane perforation].

Ugeskrift for laeger·2026
See all related articles

Calcium antagonists and digoxin can be used together, but interactions are complex. Monitoring patients is key, as dosage changes are not typically needed when starting calcium antagonists.

Area of Science:

  • Cardiology
  • Clinical Pharmacology

Context:

  • Calcium antagonists are increasingly used for various cardiovascular and non-cardiovascular conditions.
  • Concomitant use of calcium antagonists and digoxin is common in clinical practice.

Purpose:

  • To summarize the pharmacokinetics and mechanisms of potential interactions between calcium antagonists and digoxin.
  • To guide clinicians in evaluating and managing these drug interactions.

Summary:

  • Literature on calcium antagonist-digoxin interactions is inconsistent.
  • Current evidence does not support routine digoxin dose adjustments before initiating calcium antagonist therapy.
  • Monitoring pharmacodynamic parameters, serum digoxin concentration (SDC), and clinical status is recommended.

Related Experiment Videos

Impact:

  • Provides a clinical framework for managing patients on both calcium antagonists and digoxin.
  • Aims to reduce confusion and inconsistency in managing potential drug interactions.
  • Emphasizes patient monitoring over prophylactic dose changes for improved therapeutic outcomes.