[Perioperative prophylaxis in patients with head and neck tumors]

Sixty-one cancerous patients of the larynx, hipopharynx and tongue underwent surgery under perioperative prophylaxis with Cefuroxim and Metronidazole during 3 days. Alterations of the healing process could not be observed and the parameters both clinic and chemical were normal. The seric level of antibiotics was effective against most of the bacteria cultured from tracheal secretions and from the posterior wall of the oral cavity. Perioperative antibiotic prophylaxis is compulsory when major surgery is performed in head and neck.