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Related Concept Videos

lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...
Types of RNA01:20

Types of RNA

Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...
Types of RNA01:23

Types of RNA

Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Types of RNA01:23

Types of RNA

Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Types of RNA01:20

Types of RNA

Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...

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Related Experiment Video

Updated: Jun 14, 2026

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
09:36

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA

Published on: April 10, 2018

Decoding the function of nuclear long non-coding RNAs.

Ling-Ling Chen1, Gordon G Carmichael

  • 1Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, Farmington, CT 06030-3301, USA. linchen@uchc.edu

Current Opinion in Cell Biology
|April 2, 2010
PubMed
Summary
This summary is machine-generated.

Long non-coding RNAs (lncRNAs) regulate gene expression and nuclear architecture. This review highlights recent molecular-level progress in understanding lncRNA functions within the nucleus.

Related Experiment Videos

Last Updated: Jun 14, 2026

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
09:36

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA

Published on: April 10, 2018

Area of Science:

  • Molecular Biology
  • Genetics
  • Cell Biology

Background:

  • Long non-coding RNAs (lncRNAs) are transcribed across eukaryotic genomes.
  • Many lncRNAs are localized to the nucleus and implicated in gene regulation.
  • Their roles in nuclear architecture are increasingly recognized.

Purpose of the Study:

  • To review recent advancements in understanding lncRNA functions.
  • To highlight the molecular mechanisms by which lncRNAs regulate nuclear processes.
  • To provide insights into the roles of lncRNAs in gene expression and nuclear organization.

Main Methods:

  • Literature review of recent studies on lncRNAs.
  • Analysis of molecular mechanisms of lncRNA action.
  • Focus on lncRNAs involved in nuclear processes.

Main Results:

  • lncRNAs are actively involved in nuclear functions, not just passive molecules.
  • Specific lncRNAs have been shown to modulate gene expression patterns.
  • lncRNAs contribute to the structural organization of the nucleus.

Conclusions:

  • lncRNAs are key regulators of fundamental nuclear processes.
  • Understanding lncRNA mechanisms offers new avenues for research.
  • Further investigation into lncRNA roles is crucial for cell biology.