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Updated: Jun 14, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Mitral stenosis due to pannus overgrowth after rigid ring annuloplasty
Takeshi Oda1, Seiya Kato, Eiki Tayama
1Department of Surgery, Kurume University School of Medicine, Kurume-shi, Fukuoka, Japan. oda@st-mary-med.or.jp
Abstract:
Although mitral stenosis (MS) due to pannus overgrowth after mitral valve repair for rheumatic mitral regurgitation (MR) is not uncommon, it is extremely rare in relation to non-rheumatic mitral regurgitation. Whilst it has been suggested that the rigid annuloplasty ring induces pannus overgrowth in the same manner as the flexible ring, to date only in cases using the flexible ring has pannus formation been confirmed by a pathological examination after redo surgery. The case is described of a woman who had undergone mitral valve repair using a 28 mm rigid ring three years previously because of non-rheumatic MR, and subsequently suffered from MS due to pannus formation over the annuloplasty ring. To the present authors' knowledge, this is the first report of MS due to pannus formation after mitral valve repair using a rigid annuloplasty ring to treat non-rheumatic MR documented at reoperation.
Insights
Pannus overgrowth causing mitral stenosis (MS) after mitral valve repair is rare in non-rheumatic cases. This report documents the first case of MS due to pannus formation after using a rigid annuloplasty ring for non-rheumatic mitral regurgitation.
Area of Science:
- Cardiovascular Surgery
- Cardiac Pathology
Background:
- Mitral stenosis (MS) from pannus overgrowth is common after mitral valve repair for rheumatic mitral regurgitation (MR).
- Pannus formation after mitral valve repair for non-rheumatic MR is rare.
- Previous studies suggested rigid annuloplasty rings may induce pannus, but pathological confirmation was only documented with flexible rings.
Observation:
- A patient with non-rheumatic MR underwent mitral valve repair using a 28 mm rigid annuloplasty ring.
- Three years post-surgery, the patient developed MS due to pannus formation over the rigid annuloplasty ring.
Findings:
- This case represents the first documented instance of mitral stenosis caused by pannus formation following mitral valve repair with a rigid annuloplasty ring for non-rheumatic mitral regurgitation.
- Pathological examination at reoperation confirmed pannus overgrowth.
Implications:
- Highlights a rare complication of mitral valve repair using rigid annuloplasty rings in non-rheumatic MR.
- Suggests rigid rings may also contribute to pannus formation, similar to flexible rings.
- Underscores the importance of considering pannus formation in the differential diagnosis of MS after mitral valve repair, irrespective of ring type or etiology.
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