Attenuated total reflection Fourier transform infrared spectroscopy for on-chip monitoring of solute concentrations
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Updated: Jun 14, 2026

Total Internal Reflection Absorption Spectroscopy (TIRAS) for the Detection of Solvated Electrons at a Plasma-liquid Interface
Published on: January 24, 2018
Jesse Greener1, Bardia Abbasi, Eugenia Kumacheva
1Department of Chemistry, University of Toronto, 80 Saint George Street, Toronto, Ontario, Canada M5S 3H6.
Abstract:
We report a cost-efficient Attenuated Total Reflection Fourier Transform Infrared Spectroscopy (ATR-FTIR) method for monitoring concentrations of solutes in solutions flowing through microfluidic channels. The method allows rapid acquisition of spectra and enables chemical characterisation and concentration measurements that are independent of the flow rate of liquids. The method enables independent measurement of concentrations of solutes with distinct spectral features in mixed solutions. For the polymer solutes studied in the present work, the method has a sensitivity of at least 10 microM (0.01 wt%). We also propose the applicability of the method for the differentiation between dissolved and adsorbed amphiphilic species.
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