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Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment
Published on: June 23, 2019
Respiratory emergencies in HIV-infected persons
Charles K Everett1, Matthew W Fei, Laurence Huang
1Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, 505 Parnassus Avenue, Box 0111, Room M1336, San Francisco, CA 94143, USA. charles.everett@ucsf.edu
Patients with HIV often experience shortness of breath, a common emergency department complaint. This review covers diagnosing and treating diverse pulmonary emergencies in HIV-infected individuals.
Area of Science:
- Pulmonology
- Infectious Diseases
- Emergency Medicine
Background:
- Respiratory complaints are a frequent reason for emergency department (ED) visits among patients with human immunodeficiency virus (HIV) infection.
- Shortness of breath in HIV patients presents a broad differential diagnosis, encompassing both HIV-related and unrelated pulmonary conditions.
- These conditions range from minor ailments to life-threatening emergencies.
Purpose of the Study:
- To provide a comprehensive overview of respiratory emergencies in HIV-infected patients.
- To discuss the typical presentation, diagnostic evaluation, and initial therapeutic interventions for these emergencies in an ED setting.
Main Methods:
- Review of current literature on pulmonary emergencies in HIV-infected patients.
- Focus on clinical presentation, diagnostic strategies, and emergency management.
Main Results:
- The differential diagnosis for shortness of breath in HIV is extensive, including infectious (e.g., Pneumocystis pneumonia, tuberculosis) and non-infectious causes (e.g., COPD, malignancy).
- Prompt and accurate diagnosis is crucial for effective management and improved patient outcomes.
- Early initiation of appropriate therapy in the ED can significantly impact patient prognosis.
Conclusions:
- Respiratory emergencies are a critical concern for HIV-infected patients presenting to the ED.
- A systematic approach to diagnosis and management is essential for addressing the diverse range of pulmonary conditions.
- Effective ED interventions are vital for stabilizing patients and guiding further care.
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