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Updated: Jun 12, 2026

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
Published on: January 5, 2024
[Fibromyalgia diagnosis, treatment and prognosis]
Bente Danneskiold-Samsøe1, Else Marie Bartels, Kirstine Amris
1Parker Instituttet - Den Reumatologiske Forskningsenhed, Frederiksberg Hospital, 2000 Frederiksberg, Denmark. bds@frh.regionh.dk
Abstract:
It is important to recognize the diagnosis of fibromyalgia (FM) to adequately advise patients with this chronic pain disease. FM coexists with other rheumatic diseases and may therefore serve as a confounder in connection with estimation of disease activity. The aetiology and pathogenesis of FM remain unknown, although central sensitisation seems to play a major role. Following exclusion of a number of differential diagnoses, the remaining patients have several treatment options including centrally-acting medication.
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