Related Experiment Video
Updated: Jun 12, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Generic utilization and cost-sharing for prescription drugs
Teresa Bernard Gibson1, Catherine G McLaughlin, Dean G Smith
1Thomson-Reuters, Ann Arbor, MI, USA.
Increasing patient cost-sharing for brand-name drugs may not boost generic use. Instead, higher out-of-pocket costs for brand-name medications can lead to therapy discontinuation, impacting chronic disease management.
Area of Science:
- Health Economics
- Pharmaceutical Policy
- Pharmacoeconomics
Background:
- Rising healthcare costs necessitate strategies to manage prescription drug expenditures.
- Patient cost-sharing is a common tool used by health plans to influence drug utilization.
- Understanding price elasticity is crucial for designing effective cost-sharing policies.
Purpose of the Study:
- To estimate the own- and cross-price elasticity of brand-name outpatient prescription drug cost-sharing for maintenance medications.
- To assess the impact of changes in the price differential between generic and brand-name drugs on utilization.
Main Methods:
- Literature review on the effects of increased brand-name drug patient cost-sharing.
- Analysis of two empirical examples of patient filling behavior under increased brand-name cost-sharing in employer-sponsored health plans.
Main Results:
- The own-price elasticity of demand for brand-name drugs was found to be inelastic.
- Cross-price elasticity results were inconsistent in sign.
- Increased brand-name cost-sharing did not consistently lead to higher generic prescription fills.
Conclusions:
- The common strategy of increasing brand-name drug cost-sharing to promote generic use may be ineffective.
- Higher brand-name cost-sharing might lead to patients discontinuing chronic therapies rather than switching to generics.
- Findings are limited to patients with employer-sponsored health insurance.
Related Concept Videos
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Dosage Regimen: Individualization
Drug Products: Biologics, Biosimilars and Interchangeables
Drug Nomenclature
Bioequivalence of Drugs: Drugs with Multiple Indications
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence

