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Updated: Jun 11, 2026

On-Chip Octanol-Assisted Liposome Assembly for Bioengineering
Published on: March 17, 2023
"Clickable", polymerized liposomes as a versatile and stable platform for rapid optimization of their peripheral
Amit Kumar1, Uriel J Erasquin, Guoting Qin
1Department of Chemistry, University of Houston, Houston, TX 77204, USA.
None:
A versatile and stable liposomal platform is developed for rapid optimization of its peripheral composition. The platform is based on polydiacetylene lipids terminated with alkynyl groups. Conditions for copper-catalyzed azide-alkyne cycloaddition (a "click" reaction) are optimized for rapid attachment of azides with controlled composition onto the liposomes.
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