Related Experiment Video
Updated: Jun 11, 2026
12:26
Functional Site-Directed Fluorometry in Native Cells to Study Skeletal Muscle Excitability
Published on: June 2, 2023
Selective fluorescence detection of cysteine and N-terminal cysteine peptide residues
Soojin Lim1, Jorge O Escobedo, Mark Lowry
1Department of Chemistry, Portland State University, Portland, Oregon 97207, USA.
Chemical Communications (Cambridge, England)
|July 10, 2010
Abstract:
A new fluorogenic fluorescein derivative containing an alpha,beta-unsaturated aldehyde moiety produces a selective fluorescent signal enhancement in the presence of cysteine or peptides containing N-terminal cysteine residues. The mechanism is based on synergistic covalent and supramolecular interactions.
