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Updated: Jun 10, 2026
The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
Published on: February 13, 2026
Endoscopic submucosal dissection of non-polypoid colorectal neoplasms
Yutaka Saito1, Takahisa Matsuda, Takahiro Fujii
1Endoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. ytsaito@ncc.go.jp
Abstract:
Traditionally, endoscopic mucosal resection and surgery were the only available treatments for large colorectal tumors, even for those detected at an early stage. The endoscopic submucosal dissection (ESD) technique, which enables en-bloc resection of large tumors, is accepted as a standard minimally invasive treatment for early gastric cancer in Japan. This article explains in detail how ESD is performed and compares it with endoscopic mucosal resection.
