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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
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Published on: December 17, 2021

Intraocular tuberculosis.

Nicholas J Cutrufello1, Petros C Karakousis, Jane Fishler

  • 1Bascom Palmer Eye Institute, Department of Ophthalmology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.

Ocular Immunology and Inflammation
|July 29, 2010
PubMed
Summary
This summary is machine-generated.

Intraocular tuberculosis (TB) is rare but globally significant. This review details diagnosing and managing eye TB, focusing on diagnostic tests and treatments for all patients, including those with compromised immunity.

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Published on: February 6, 2021

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Public Health

Background:

  • Tuberculosis (TB) infection is globally prevalent, particularly in developing nations and among specific populations in developed countries.
  • Intraocular manifestations of TB are uncommon but pose diagnostic and therapeutic challenges.
  • Increased incidence observed in immigrant and immunocompromised individuals necessitates focused clinical attention.

Purpose of the Study:

  • To review the clinical characteristics of intraocular tuberculosis.
  • To discuss current diagnostic modalities for intraocular TB.
  • To outline management strategies, including special considerations for immunocompromised patients.

Main Methods:

  • Review of literature on intraocular tuberculosis.
  • Discussion of diagnostic techniques: Interferon-gamma Release Assays (IGRAs), antigen-detection assays, and polymerase chain reactions (PCR).
  • Analysis of treatment protocols, including anti-tuberculous medications, corticosteroids, and HIV co-infection management.

Main Results:

  • Intraocular TB diagnosis relies on a combination of clinical presentation and laboratory findings.
  • IGRAs, antigen-detection assays, and PCR offer valuable tools for identifying TB infection.
  • Management requires a multi-faceted approach, integrating anti-TB therapy with supportive care.

Conclusions:

  • Early and accurate diagnosis of intraocular TB is crucial for effective management and visual preservation.
  • Diagnostic advancements are improving the identification of ocular TB.
  • Comprehensive management, including addressing co-morbidities like HIV, is essential for successful outcomes in intraocular TB patients.