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Ex vivo Culture of Human Placental Explants for the Study of Viral Transmission Across the Maternal-Fetal Interface
Published on: December 30, 2025
Selected viral infections in pregnancy
Britta Panda1, Alexander Panda, Laura E Riley
1Division of Maternal Fetal Medicine, Massachusetts General Hospital, 55 Fruit Street, Founders 450, Boston, MA 02210, USA.
Obstetrics and Gynecology Clinics of North America
|August 6, 2010
Summary
This review covers seasonal influenza and the 2009 H1N1 pandemic
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Public Health
Background:
- Seasonal influenza poses significant risks to pregnant individuals.
- The 2009 novel H1N1 pandemic highlighted these risks.
- Hepatitis A, B, and C infections also present challenges during pregnancy.
Purpose of the Study:
- To review the impact of seasonal influenza on pregnancy.
- To discuss antiviral therapies and vaccination for influenza in pregnancy.
- To address prevention and treatment of hepatitis B and C in pregnant individuals.
Main Methods:
- Literature review of seasonal influenza and pregnancy.
- Review of 2009 H1N1 pandemic data in pregnant populations.
- Analysis of current guidelines for influenza and hepatitis management in pregnancy.
Main Results:
- Influenza vaccination is recommended and safe for pregnant individuals.
- Antiviral treatment is crucial for pregnant women with influenza.
- Effective prevention and treatment strategies exist for hepatitis B and C.
Conclusions:
- Pregnant women are a vulnerable group for influenza and require specific management.
- Vaccination and prompt antiviral therapy are key for influenza prevention and treatment.
- Hepatitis B and C require tailored management strategies in pregnancy.
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