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Updated: Jun 10, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
Myocardial tissue Doppler velocity imaging in children: comparative study between two ultrasound systems
Laurens P Koopman1, Cameron Slorach, Cedric Manlhiot
1Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Insights
Pulsed-wave tissue Doppler (PWTD) showed good agreement between GE and Philips ultrasound systems. Color tissue Doppler (CTD) velocities, however, differed significantly between the two systems, indicating potential variability in pediatric cardiac assessments.
Area of Science:
- Pediatric Cardiology
- Echocardiography
- Ultrasound Technology
Background:
- Ventricular tissue Doppler imaging (TDI) is crucial for assessing cardiac function in children.
- Comparing different ultrasound systems is essential for standardizing measurements.
- Interobserver and intraobserver variability are key factors in diagnostic accuracy.
Purpose of the Study:
- To compare pulsed-wave tissue Doppler (PWTD) and color tissue Doppler (CTD) ventricular tissue velocities between GE Vivid 7 and Philips iE33 ultrasound systems.
- To evaluate the interobserver and intraobserver variability of these measurements.
- To assess the agreement of TDI-derived velocities across different echocardiography platforms.
Main Methods:
- Prospective acquisition of longitudinal PWTD and CTD images in 49 children.
- Measurements were taken from the right and left ventricular free wall and septum.
- Offline analysis was performed to determine velocity measurements and variability coefficients.
Main Results:
- PWTD velocities demonstrated reasonable agreement between GE and Philips systems, with low coefficients of variation (1-14%).
- CTD velocities showed substantial differences between GE and Philips systems, with higher coefficients of variation (4-25%).
- System-specific biases were noted, with CTD-derived peak velocities being consistently lower on the Philips system.
Conclusions:
- PWTD is a reliable method for assessing ventricular velocities across GE and Philips ultrasound platforms in pediatric populations.
- CTD measurements exhibit significant inter-system variability, necessitating caution when comparing data from different manufacturers.
- Standardization of CTD acquisition and analysis protocols may be required to improve consistency in pediatric cardiac assessments.
Background:
The investigators compared pulsed-wave tissue Doppler (PWTD) and color tissue Doppler (CTD) ventricular tissue velocities obtained using Vivid 7 (GE) and iE33 (Philips) ultrasound systems within a 30-minute time frame and examined interobserver and intraobserver variability.
Methods:
Longitudinal PWTD and CTD images were prospectively acquired in 49 children from the base of the right and left ventricular free wall and septum and stored for offline analysis.
Results:
Intraobserver and interobserver coefficients of variation for PWTD velocities ranged from 4% to 6% and 5% to 10% for GE and from 1% to 10% and 2% to 14% for Philips, respectively. Intraobserver and interobserver coefficients of variation for CTD velocities ranged from 4% to 15% and 6% to 24% for GE and from 6% to 19% and 7% to 25% for Philips, respectively. Mean biases between the two systems for PWTD velocities, expressed as percentage differences, were around 0%, with the narrowest limits of agreement for systolic velocities at the septal annulus and the widest limits of agreement for early diastolic velocities at the lateral tricuspid valve annulus, respectively. Peak CTD-derived velocities were significantly and consistently lower for Philips compared with GE.
Conclusions:
Agreement between GE-derived and Philips-derived PWTD velocities was reasonable, whereas CTD-derived velocities differed substantially.
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