Related Experiment Video
Updated: Jun 10, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Acute stroke management
1Stroke Center, Methodist University Hospital, Memphis, TN 38104, USA.
Insights
Stroke is a leading cause of death and disability. Acute ischemic stroke, a common emergency, is treatable with therapies like tissue plasminogen activator (TPA), though management controversies persist.
Area of Science:
- Neurology
- Cardiovascular Medicine
- Public Health
Background:
- Stroke is the third leading cause of death and the primary cause of long-term disability in the U.S.
- Major stroke types include ischemic (85% of cases) and hemorrhagic, both causing brain cell death due to inadequate blood/oxygen supply.
- Acute ischemic stroke is a medical emergency, but advancements like TPA approval in 1995 offer treatment options.
Purpose of the Study:
- To discuss major issues and controversies in the acute management of stroke.
- To highlight the importance of timely and effective stroke interventions.
- To provide an overview of current challenges in stroke care.
Main Methods:
- Review of existing literature on stroke management.
- Analysis of current treatment protocols and guidelines.
- Discussion of unresolved questions in acute stroke care.
Main Results:
- Acute ischemic stroke management remains a complex field with ongoing debates.
- The efficacy of TPA has improved outcomes, but its application and timing are critical.
- Variations in stroke etiology and location necessitate tailored management strategies.
Conclusions:
- Effective acute stroke management requires addressing current controversies and refining treatment approaches.
- Continued research and discussion are essential for optimizing patient outcomes.
- Improving stroke care is crucial for reducing mortality and long-term disability.
Abstract:
Extract: Stroke is the third leading cause of death in the United States, coming in just behind cancer and coronary artery disease. It is, however, the leading cause of long-term disability. Stroke includes two major categories -- ischemic and hemorrhagic stroke (reduced blood supply and blood leakage, respectively), which both lead to a lack of adequate blood and oxygen supply to brain tissue, resulting in cell death. About 85% of strokes are ischemic. Ischemic strokes can also be divided into different categories based on their etiology and location. Acute ischemic stroke is an emergency, but a treatable condition especially since the TPA (tissue plasminogen activator, which is also a natural substance that helps dissolve blood clots in blood circulation) was approved by the U.S. FDA in 1995. Even though acute strokes are very common, there are still a lot of controversies about their acute management. Some of the major issues with regard to acute management of strokes are discussed here.
Related Concept Videos
Atherosclerosis IV: Nursing Management
Acute Coronary Syndrome IV: Interprofessional Care
Ischemic Stroke ll: Pathophysiology
Ischemic Stroke l: Introduction
Hemorrhagic Stroke l: Introduction
Stroke: Introduction and Types
