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Updated: Jun 9, 2026

14:37
High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
Published on: July 6, 2012
Methods for the functionalisation of nanoparticles: new insights and perspectives
Thomas Perrier1, Patrick Saulnier, Jean-Pierre Benoît
1INSERM U646, Angers University, 10, rue André Boquel, France. thomas.perrier2@hotmail.fr
Chemistry (Weinheim an Der Bergstrasse, Germany)
|August 31, 2010
Summary
Surface engineering of nanometre-sized drug-delivery systems is crucial for desired properties. This review summarizes techniques for tailoring particle surfaces, guiding future research in this expanding field.
Area of Science:
- Materials Science
- Nanotechnology
- Pharmaceutical Sciences
Background:
- Diverse colloidal systems exist for nanometre-sized drug delivery.
- These systems share a core-shell structure with an inner part and an external surface.
- The particle surface is critical for functionality and future development.
Purpose of the Study:
- To review and summarize techniques for engineering the surfaces of nanometre-sized drug-delivery systems.
- To highlight recent advancements in surface modification methods.
- To provide a foundation for future research in this area.
Main Methods:
- Literature review of existing techniques.
- Focus on surface engineering approaches for colloidal drug delivery systems.
- Analysis of recent advancements in the field.
Main Results:
- Identification of various surface engineering techniques applicable to nanodrug delivery systems.
- Summary of the state-of-the-art in particle surface modification.
- Highlighting the importance of surface properties for system performance.
Conclusions:
- Surface engineering is a key emerging step in designing nanometre-scale drug delivery systems.
- A comprehensive understanding of available techniques is essential for innovation.
- This review serves as a valuable resource for researchers in nanomedicine and materials science.

