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Percutaneous cholecystostomy (PC) in the management of acute cholecystitis in high risk patients
Shaista Afzal Saeed1, Imrana Masroor
1Department of Radiology, The Aga Khan University Hospital, Stadium Road, Karachi. shaista.afzal@aku.edu
Insights
Ultrasound-guided percutaneous cholecystostomy (PC) is a safe and effective treatment for acute cholecystitis in high-risk patients. This procedure offers a favorable clinical response and low complication rates, providing an alternative to immediate surgery.
Area of Science:
- Gastroenterology
- Interventional Radiology
- Surgical Oncology
Background:
- Acute cholecystitis management in high-risk patients presents challenges.
- Conservative management may fail in select cases.
- Percutaneous cholecystostomy (PC) is an alternative for non-resolving acute cholecystitis.
Purpose of the Study:
- To evaluate the role of ultrasound-guided PC in managing acute cholecystitis.
- To assess complications and outcomes in high-risk surgical patients.
- To determine PC's efficacy in cases unresponsive to conservative treatment.
Main Methods:
- Observational case series conducted at The Aga Khan University Hospital from 2003-2007.
- Included patients with acute cholecystitis unfit for immediate surgery and unresponsive to conservative management.
- Ultrasound-guided PC was performed; variables included demographics, comorbidities, ultrasound findings, procedure details, complications, and clinical outcomes (48 hours and 30 days).
Main Results:
- Forty-one patients (15 males, 26 females; mean age 65 years) were studied.
- Indications included calculus cholecystitis (25), acalculous cholecystitis (10), empyema (4), and gallbladder perforation (2).
- No procedure-related complications occurred in 75% of patients; 83% showed favorable clinical response. Mortality was 12% due to underlying conditions, with no direct procedure-related deaths.
Conclusions:
- Ultrasound-guided PC is a safe and effective procedure for immediate management of acute cholecystitis in high-risk patients.
- It offers a viable alternative for patients not responding to conservative treatment and unfit for surgery.
- The procedure demonstrates a low complication rate and positive clinical outcomes.
Objective:
To determine the role of ultrasound-guided percutaneous cholecystostomy (PC) regarding complications and outcome in the management of acute cholecystitis in patients high risk for surgery and anaesthesia and not responding to conservative management.
Study Design:
Observational case series.
Place And Duration Of Study:
The study was carried out at The Aga Khan University Hospital, Karachi, from January 2003 to December 2007.
Methodology:
The study included patients admitted with acute cholecystitis considered unfit for immediate surgery but not responding to conservative management. Percutaneous cholecystostomy was conducted under ultrasound guidance. The studied variables included patients' demographics, co-morbid, ultrasound findings of biliary tree, indication for percutaneous cholecystostomy, its route, complication during or after procedure, patient's clinical outcome (upto 48 hours) and 30 days follow-up. Those with incomplete medical record and follow-up were excluded. Data were analyzed and results compiled using SPSS 16.0 version. Mean and standard deviation for quantitative variable like age was derived. Proportions were computed for complications and patient's clinical outcome.
Results:
Forty one patients with complete medical record were studied including 15 (37%) males and 26 (63%) females. Mean age was 65 +/-13.5 years. Indications for PC included calculus cholecystitis in 25, acalculous cholecystitis in 10, empyema in 04 and gallbladder perforation in 02 patients. No complication was seen during or after procedure in 31 (75%) patients. Complications occurred in 10 (25%) patients including vagal reaction, pain during procedure, tube blockage, catheter dislodgement and bile leakage. Favourable clinical response (improvement in clinical symptoms) was noted in 34 (83%) patients. Seven (17%) patients did not show any improvement in clinical condition after the procedure. On 30 days follow-up, 9 patients had undergone cholecystectomy, 5 (12%) patients expired due to underlying clinical conditions and the rest were settled without requiring an immediate cholecystectomy. There was no direct procedure-related mortality.
Conclusion:
Imaging guided PC is a safe and effective procedure for immediate management of non-resolving acute cholecystitis in patients high risk for surgery and anaesthesia and not responding to conservative management.
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