Related Experiment Video

Updated: Jun 8, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
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An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)

Published on: January 27, 2010

Local anesthetic use in the pregnant and postpartum patient

Edgar P Fayans1, Hunter R Stuart, David Carsten

  • 1Dental Anesthesiology Residency, Lutheran Medical Center, Brooklyn, NY 11220, USA. efayans@hotmail.com

Dental Clinics of North America
|September 14, 2010
PubMed

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Local Anesthetics: Common Agents and Their Applications

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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