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Related Experiment Video

Updated: Jun 8, 2026

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

Published on: April 18, 2013

Multisensor smart system on a chip.

Louiza Sellami¹, Robert W Newcomb

¹Electrical and Computer Engineering Department, US Naval Academy, Annapolis, MD 21401, USA. sellami@usna.edu

Advances in Experimental Medicine and Biology

|September 25, 2010

Summary

This summary is machine-generated.

This study introduces a novel multisensor system on a chip for healthcare applications. The developed transistorized biosensor enables precise fluid analysis for potential in-home kidney function monitoring.

Related Experiment Videos

Last Updated: Jun 8, 2026

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

Published on: April 18, 2013

Area of Science:

Biomedical Engineering
Sensor Technology
Microelectromechanical Systems (MEMS)

Background:

The increasing importance of sensors in healthcare necessitates the development of advanced, integrated sensing solutions.
Existing sensors often lack miniaturization, cost-effectiveness, and on-chip integration of control and analysis functionalities.
Microelectromechanical systems (MEMS) offer a platform for creating miniaturized sensors with integrated signal processing.

Purpose of the Study:

To present a general framework for designing a multisensor system on a chip (SoC).
To develop an intelligent signal processing framework with built-in self-test and parameter adjustment capabilities.
To create a transistorized bridge biosensor for monitoring dielectric constant changes in fluids.

Main Methods:

System architecture design for a multisensor SoC.
Development of a transistorized bridge biosensor.
Integration of signal processing, self-test, and parameter adjustment units onto a single chip.

Main Results:

A general framework for multisensor SoC design was established.
A functional transistorized bridge biosensor was developed.
The biosensor is capable of monitoring dielectric constant changes in fluids.

Conclusions:

The developed multisensor SoC framework facilitates the creation of sophisticated, integrated sensing devices.
The transistorized bridge biosensor shows promise for non-invasive, in-home monitoring of critical physiological parameters.
This technology could significantly aid in the management of chronic conditions like renal failure.