Related Experiment Videos
Polymorphisms of the regulators of complement activation gene cluster
D Hourcade1, T W Post, V M Holers
1Howard Hughes Medical Institute Laboratories, Department of Medicine, Washington University, St. Louis, Mo.
Complement and Inflammation
|January 1, 1990
Abstract:
The regulators of complement activation (RCA) constitute a tightly linked gene family that controls the activity of the complement system. Genetic polymorphisms have been reported for all of RCA genes at the DNA, RNA and/or protein levels. In addition, multiple RNA and/or protein products have been observed for most of these genes. These polymorphisms and variants are instrumental in the study of the structure, evolution and function of the RCA family.